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KMID : 1025520110530040311
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Journal of Animal Science and Technology
2011 Volume.53 No. 4 p.311 ~ p.317
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Association between the Polymorphism of the Fatty acid binding protein 5 (FABP5) Gene within the BTA 14 QTL Region and Carcass/Meat Quality Traits in Hanwoo
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Heo Kang-Nyeong
Kim Nam-Kuk
Lee Seung-Hwan
Kim Nam-Young
Jeon Jin-Tae
Park Eung-Woo
Oh Sung-Jong
Kim Tae-Hun
Seong Hwan-Hoo
Yoon Du-Hak
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Abstract
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The aim of this study was to evaluate the association between economic traits of Korean cattle (Hanwoo) and genetic variation in fatty acid binding protein 5 (FABP5) gene within QTL region of carcass weight and marbling score traits on BTA 14. We sequenced for detection of single nucleotide polymorphism (SNP) with 24 unrelated Hanwoo samples and identified four SNPs (-1141A>G, 949A>G, 969A>G and 1085C>G). Relationship between the genotypes of 583 Hanwoo individuals by PCR-RFLP and economic traits were analyzed by the mixed regression model implemented in the ASReml program. As the result of statistical analysis, SNP1 (-1141A>G) showed significant effect (p<0.003) on marbling score (MS) and SNP2 (949A>G) showed significant effect (p<0.034) on eye muscle area (EMA). Further studies are required to validate the significant SNPs in a bigger population, but the SNPs (-1141A>G and 949A>G) of FABP5 could be a genetic marker to estimate molecular breeding value (MEBV) for carcass traits in Hanwoo.
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KEYWORD
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Hanwoo, FABP5, SNP, PCR-RFLP
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